Central centrifugal cicatricial alopecia severity is associated with cowhage-induced itch

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Central centrifugal cicatricial alopecia: challenges and solutions

Central centrifugal cicatricial alopecia (CCCA) is the most common scarring alopecia among African American women. Data about epidemiology, etiology, genetic inheritance, and management are scarce and come from individual reports or small series. CCCA has been associated with hot combing and traumatic hair styling for years; however, studies fail to confirm it as the sole etiologic factor. It h...

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Central centrifugal cicatricial alopecia - an approach to diagnosis and management.

Central centrifugal cicatricial alopecia (CCCA) occurs primarily in African-American women and is the most common cause of scarring hair loss in this population. Since the mid 20th century, hair care practices of African-American women have been associated with CCCA, although there is developing evidence that the etiology of CCCA may be multifactorial. Clinically diagnosing CCCA may be challeng...

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Central Centrifugal Cicatricial Alopecia Presenting with Irregular Patchy Alopecia on the Lateral and Posterior Scalp.

BACKGROUND Central centrifugal cicatricial alopecia (CCCA) is the most common cause of scarring alopecia among women of African descent which affects the central scalp and spreads centrifugally but spares the lateral and posterior scalp. OBJECTIVES The objective of this study is to report on a new clinical variety of CCCA presenting with patchy alopecia involving the lateral and posterior sca...

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Cowhage-Induced Itch as an Experimental Model for Pruritus. A Comparative Study with Histamine-Induced Itch

BACKGROUND Histamine is the prototypical pruritogen used in experimental itch induction. However, in most chronic pruritic diseases, itch is not predominantly mediated by histamine. Cowhage-induced itch, on the other hand, seems more characteristic of itch occurring in chronic pruritic diseases. OBJECTIVES We tested the validity of cowhage as an itch-inducing agent by contrasting it with the ...

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Medical and environmental risk factors for the development of central centrifugal cicatricial alopecia: a population study.

OBJECTIVE To investigate medical and environmental risk factors for central centrifugal cicatricial alopecia (CCCA), the most common type of scarring alopecia in African American women. DESIGN A population study involving a quantitative cross-sectional survey of risk factors for CCCA. Survey results are then correlated with a clinical evaluation for CCCA using a standardized, previously publi...

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ژورنال

عنوان ژورنال: British Journal of Dermatology

سال: 2013

ISSN: 0007-0963

DOI: 10.1111/bjd.12043